Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
Estroneacetate
Cat.No.:HY-111182
CASNo.:901-93-9
Synonyms:Hogival;Oestrone-3-acetate;Puboestrene
分?式:C??H??O?
分?量:312.4
作?靶点:EstrogenReceptor/ERR
作?通路:VitaminDRelated/NuclearReceptor
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Estroneacetate(Hogival)是?种雌激素衍?物,是雌激素受体(ER)激活剂。Estroneacetate能够促进乳腺发
育、刺激垂体泌乳素(prolactin)分泌,以及诱导泌乳细胞(lactotrophs)的增殖与活化(如降低泌乳素储存颗粒
??,同时增加粗?内质?和?尔基体体积密度)。Estroneacetate有望?于内分泌学研究,以及探究雌激素
影响垂体功能、泌乳素调控及乳腺肿瘤模型的机制[1]。
REFERENCES
[1].McCombDJ,etal.Enhancedresponsivenessoflactotrophsinectopicpituitariestobromocryptineandestroneacetate.ActaAnat
(Basel).1981;110(2):113-20.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
1/1