基本信息
文件名称：FCCP-Standard-Carbonyl-cyanide-4-trifluoromethoxy-phenylhydrazone-Standard-生命科学试剂-MCE.pdf
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

FCCP(Standard)

Cat.No.:HY-100410R

CASNo.:370-86-5

Synonyms:Carbonylcyanide4-(trifluoromethoxy)phenylhydrazone

(Standard)

分?式:C??H?F?N?O

分?量:254.17

作?靶点:OxidativePhosphorylation;PINK1/Parkin;Mitochondrial

Metabolism

作?通路:MetabolicEnzyme/Protease;Autophagy;NeuronalSignaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性FCCP(Standard)是FCCP的分析标准品。本产品?于研究及分析应?。FCCP是线粒体中氧化磷酸化(

OXPHOS)解偶联剂。FCCP诱导PINK1激活，促进Parkin在Ser65位点磷酸化[1]。

REFERENCES

[1].ConnopBPetal.NoveleffectsofFCCP[carbonylcyanidep-(trifluoromethoxy)phenylhydrazone]onamyloidprecursorprotein

processing.JNeurochem.1999Apr;72(4):1457-65.

[2].TanpraditN,etal.Carbonylcyanide4-(trifluoromethoxy)phenylhydrazone(FCCP)pre-exposureensuresfollicleintegrityduringinvitro

cultureofovariantissuebutnotduringcryopreservationinthedomesticcatmodel.JAssistReprodGenet.2016Dec;33(12):1621-1631.

Epub2016Sep