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Inhibitors?ScreeningLibraries?Proteins
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STING-IN-14
Cat.No.:HY-173326
CASNo.:3070953-78-2
分?式:C??H??F?N??O?
分?量:867.9
作?靶点:STING
作?通路:Immunology/Inflammation
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性STING-IN-14是?种STING抑制剂(IC50:0.6nM)。STING-IN-14抑制THP1-DualTM细胞IRF通路的激活。
STING-IN-14可?于??免疫性疾病的研究。
体外研究STING-IN-14(Example50)(20-24h)inhibitstheactivationofIRFpathwayinTHP1-DualTMcells(IC50:2
nM)[1].
REFERENCES
[1].1.HanX,etal.Macrocyclesforthetreatmentofautoimmunediseaseandtheirpreparation.WO2025021666.F.Hoffmann-LaRoche
AG,Switzerland.2025-01-30.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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