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Roxindolehydrochloride(Standard)

Cat.No.:HY-106100AR

CASNo.:108050-82-4

Synonyms:EMD38362(Standard)

分?式:C??H??ClN?O

分?量:382.93

作?靶点:DopamineReceptor;SerotoninTransporter

作?通路:GPCR/GProtein;NeuronalSignaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Roxindole(hydrochloride)(Standard)是Roxindole(hydrochloride)的分析标准品。本产品?于研究及分析应

?。Roxindolehydrochloride，?种吲哚烷基哌啶，是多巴胺??受体(dopamineautoreceptors)的有效激

动剂，在低纳摩尔范围内与D2样亚型具有亲和?。Roxindolehydrochloride可?于研究阳性和阴性精神分裂

症症状。Roxindolehydrochloride是5-HT1A激动剂和5-羟?胺(5-HT)的摄取的抑制剂。具有抗精神病药和

抗抑郁药活性。

REFERENCES

[1].BartoszykGD,HartingJ,MinckKO.Roxindole:psychopharmacologicalprofileofadopamineD2autoreceptoragonist.JPharmacolExp

Ther.1996;276(1):41-48.

[2].WetzelH,etal.Roxindole,adopamineautoreceptoragonist,inthetreatmentofpositiveandnegativeschizophrenicsymptoms.AmJ

Psychiatry.1994;151(10):1499-1502.

[3].MajJ,etal.Roxind