基本信息
文件名称:MNN-02-155-生命科学试剂-MCE.pdf
文件大小:458.28 KB
总页数:1 页
更新时间:2025-05-23
总字数:约1.92千字
文档摘要

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Inhibitors?ScreeningLibraries?Proteins

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MNN-02-155

Cat.No.:HY-173641

CASNo.:3067681-22-2

分?式:C??H??ClF?N??O?

分?量:1136.69

作?靶点:MolecularGlues;HistoneAcetyltransferase;BCL6

作?通路:PROTAC;Epigenetics;Immunology/Inflammation

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性MNN-02-155是?种?价分?胶(molecularglue),可与p300/CBP和BCL6双重结合。MNN-02-155可诱导

BCL6靶向报告基因的强效激活和细胞死亡。MNN-02-155可?于研究弥漫性?B细胞淋巴瘤(DLBCL)[1]。

REFERENCES

[1].NixMN,etal.ABivalentMolecularGlueLinkingLysineAcetyltransferasestoOncogene-inducedCellDeath.bioRxiv[Preprint].2025

Mar17:2025.03.14.643404.

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