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epi-D-Captopril

Cat.No.:HY-B0368C

CASNo.:112243-88-6

Synonyms:epi-D-SQ14225

分?式:C?H??NO?S

分?量:217.29

作?靶点:Beta-lactamase

作?通路:Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性epi-D-Captopril(epi-D-SQ14225)是Captopril(HY-B0368)的?种?体异构体，是?属β-内酰胺酶(MBLs)

抑制剂。epi-D-Captopril对NDM-1、IMP-1、VIM-2的IC50分别为64μM、173μM和5.5μM。epi-D-

Captopril有望?于MBLs相关的耐药菌感染疾病领域的研究[1]。

REFERENCES

[1].BremJ,etal.StructuralBasisofMetallo-β-LactamaseInhibitionbyCaptoprilStereoisomers.AntimicrobAgentsChemother.2015Oct

19;60(1):142-50.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师