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Cypermethrin
Cat.No.:HY-B0829
CASNo.:52315-07-8
分?式:C??H??Cl?NO?
分?量:416.3
作?靶点:SodiumChannel;ChlorideChannel;PotassiumChannel;
CalciumChannel;nAChR
作?通路:MembraneTransporter/IonChannel;NeuronalSignaling
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Cypermethrin是?种可穿透?脑屏障(BBB)的II类拟除?菊酯类农药。Cypermethrin具有神经毒性，并会导
致运动功能障碍。Cypermethrin会延长(钠离?通道)的开放时间，使中枢神经系统过度兴奋。通过调节(氯离
?通道)、(钙离?通道)和(钾离?通道)，并影响?氨酸受体和?酰胆碱受体，Cypermethrin会在神经元中引
发DNA损伤和氧化应激。此外，Cypermethrin还会调节γ-氨基丁酸和多巴胺等神经递质的?平。
REFERENCES
[1].SinghAK,etal.Acurrentreviewofcypermethrin-inducedneurotoxicityandnigrostriataldopaminergicneurodegeneration.Curr
Neuropharmacol.2012Mar;10(1):64-71.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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