Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Andolastfreebase(Standard)

Cat.No.:HY-106358R

CASNo.:132640-22-3

Synonyms:CR2039freebase(Standard);Dizolastfreebase(Standard)

分?式:C??H??N?O

分?量:333.31

作?靶点:Phosphodiesterase(PDE)

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Andolast(freebase)(Standard)是Andolast(freebase)的分析标准品。本产品?于研究及分析应?。

Andolast(CR2039)(freebase)是?种抗过敏剂。Andolast可抑制cAMP-磷酸?酯酶，IC50值为50μM。

Andolast可?于哮喘的研究。

REFERENCES

[1].RevelL,ColomboS,FerrariF,FolcoG,RovatiLC,MakovecF.CR2039,anewbis-(1H-tetrazol-5-yl)phenylbenzamidederivativewith

potentialforthetopicaltreatmentofasthma.EurJPharmacol.1992;229(1):45-53.

[2].CzuczwarSJ,GasiorM,KozickaM,PietrasiewiczT,TurskiWA,KleinrokZ.Apotentialanti-asthmaticdrug,CR2039,enhancesthe

anticonvulsiveactivityofsomeantiepilepticdrugsagainstpentetrazolinmice.EurNeuropsychopharmacol.1998;8(3):233-238.

McePdfHeight

Caution:Producthasnotb