Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

9-Hydroxyellipticinehydrochloride(Standard)

Cat.No.:HY-101775AR

CASNo.:52238-35-4

分?式:C??H??ClN?O

分?量:298.77

作?靶点:Topoisomerase

作?通路:CellCycle/DNADamage

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性9-Hydroxyellipticine(hydrochloride)(Standard)是9-Hydroxyellipticine(hydrochloride)的分析标准品。本

产品?于研究及分析应?。9-Hydroxyellipticinehydrochloride是TopoII和RyR的抑制剂。9-

Hydroxyellipticinehydrochloride具有抗肿瘤、抗氧化和释放?茶酚胺的活性。9-Hydroxyellipticine

hydrochloride对HelaS-3和293T细胞的IC50值分别为1.6μM和1.2μM。

REFERENCES

[1].RenaultG,etal.Invivoexposuretofourellipticinederivativeswithtopoisomeraseinhibitoryactivityresultsinchromosomeclumping

andsisterchromatidexchangeinmurinebonemarrowcells.ToxicolApplPharmacol.1987Jun30;89(2):281-6.

[2].SaekiK,etal.Cardioprotectiveeffectsof9-hydroxyellipticineonischemiaandreperfusioninisolatedratheart.JpnJPharmacol.2002

May;89(1):21-8.

[3].GRenault,etal.Invivoexposuretofourelliptic