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FtsZ-IN-13
Cat.No.:HY-173277
CASNo.:914357-88-3
分?式:C??H??N?O?S?
分?量:386.44
作?靶点:Bacterial
作?通路:Anti-infection
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性FtsZ-IN-13(CompoundC11)是温度敏感突变体Z(FtsZ)的抑制剂，对FtsZSa和FtsZPa的IC50值分别为
47.97和34μM。FtsZ-IN-13对?黄?葡萄球菌(最低抑菌浓度为2μg/mL)、囊性纤维化?黄?葡萄球菌临
床分离株和耐甲氧西林?黄?葡萄球菌(MRSA)均具有显著的抗菌活性。FtsZ-IN-13可?于抗菌素耐药性研究
[1]。
REFERENCES
[1].SciòP,etal.IdentificationofaNewFtsZInhibitorbyVirtualScreening,MechanisticInsights,andStructure-ActivityRelationship
Analyses.ACSInfectDis.2025Apr11;11(4):998-1007.
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