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Inhibitors?ScreeningLibraries?Proteins

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FAPtargetingpeptide-PEG2conjugate

Cat.No.:HY-P10946

CASNo.:3076328-71-4

分?式:C??H???N??O??

分?量:1491.69

作?靶点:Radionuclide-DrugConjugates(RDCs)

作?通路:Antibody-drugConjugate/ADCRelated

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性FAPtargetingpeptide-PEG2conjugate(ExampleA1)是UnlabeledFXX489(HY-P10944)的多肽(HY-

P10945)和linker偶联物部分。UnlabeledFXX489(HY-P10944)是?种成纤维细胞活化蛋?(FAP)靶向配体。

REFERENCES

[1].RavitGeva,etal.AbstractCT112:PhaseIopen-label,multi-centerstudytoevaluatethesafety,tolerability,dosimetry,andpreliminary

activityofFXX489([177Lu]Lu-NNS309)inpatientswithpancreatic,lung,breastandcolorectalcancers.CancerRes(2025)85

(8_Supplement_2):CT112.

[2].SalvatoreBONGARZONE,etal.Faptargetingcyclicpeptidesandconjugatesthereof.WO2025037249A1.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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