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Inhibitors?ScreeningLibraries?Proteins

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Acemetacin-13C6

Cat.No.:HY-B0482S1

Synonyms:TVX1322-13C6

分?式:C????C?H??ClNO?

分?量:417.75

作?靶点:Isotope-LabeledCompounds;COX

作?通路:Others;Immunology/Inflammation

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Acemetacin-13C6(TVX1322-13C6)是13C标记的Acemetacin.Acemetacin(TVX1322)是?甾体抗炎类化合

物。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].TavaresIA,etal.Non-steroidalanti-inflammatorydrugsthatcauserelativelylittlegastricdamage.JGastroenterolHepatol.1998

Nov;13(S3):S190-S192.

McePdfHeight