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Chenodeoxycholicacid24-acyl-β-D-glucuronide-d5sodium

Cat.No.:HY-W756134

分?式:C??H??D?NaO??

分?量:595.71

作?靶点:Isotope-LabeledCompounds;DrugMetabolite;FXR

作?通路:Others;MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Chenodeoxycholicacid24-acyl-β-D-glucuronide-d5sodium是Chenodeoxycholicacid24-acyl-β-D-

glucuronidesodium的氘代物。Chenodeoxycholicacid24-acyl-β-D-glucuronidesodium是

ChenodeoxycholicAcid(HY-76847)的代谢产物。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].CaronP,etal.EnzymaticproductionofbileAcidglucuronidesusedasanalyticalstandardsforliquidchromatography-mass

spectrometryanalyses.MolPharm.2006May-Jun;3(3):293-302.

McePdfHeight