Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Cyclo(his-pro)TFA(Standard)

Cat.No.:HY-101402AR

CASNo.:936749-56-3

Synonyms:Cyclo(histidyl-proline)TFA(Standard);Histidylproline

diketopiperazineTFA(Standard)

分?式:C??H??F?N?O?

分?量:348.28

作?靶点:NF-κB;EndogenousMetabolite

作?通路:NF-κB;MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Cyclo(his-pro)(TFA)(Standard)是Cyclo(his-pro)(TFA)的分析标准品。本产品?于研究及分析应?。

Cyclo(his-pro)TFA(Cyclo(histidyl-proline)TFA)是?种具有?服活性的，结构上与促甲状腺激素释放激素相

关的环状?肽。Cyclo(his-pro)TFA可以抑制NF-κB核积累。Cyclo(his-pro)TFA可以穿越脑?屏障并影响多

种炎症和应激反应。

REFERENCES

[1].GrottelliS,etal.TheRoleofCyclo(His-Pro)inNeurodegeneration.IntJMolSci.2016Aug12;17(8).pii:E1332.

[2].MinelliA,etal.Cyclo(His-Pro)exertsanti-inflammatoryeffectsbymodulatingNF-κBandNrf2signalling.IntJBiochemCellBiol.2012

Mar;44(3):525-35.

[3].BellezzaI,etal.Neuroinflammationandendoplasmicreticulumstressarecoregulatedby