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Inhibitors?ScreeningLibraries?Proteins

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CYP19A1-IN-1

Cat.No.:HY-173279

CASNo.:889959-22-2

分?式:C??H??ClN?O?

分?量:393.82

作?靶点:CytochromeP450

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性CYP19A1-IN-1(Compound9)是?种CYP19A1抑制剂，IC50为271nM。CYP19A1-IN-1通过与CYP19A1结

合，来抑制其将雄激素转化为雌激素的活性。CYP19A1-IN-1可?于雌激素依赖型乳腺癌等性激素相关疾病的

研究[1]。

REFERENCES

[1].LiuS,etal.IntegratedVirtualScreeningApproachIdentifiesNewCYP19A1Inhibitors.JChemInfModel.2025Mar19.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师