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ReportontheDeliberationResults

March10,2015

EvaluationandLicensingDivision,PharmaceuticalandFoodSafetyBureau

MinistryofHealth,LabourandWelfare

[Brandname]NovoThirteen2500IUforIntravenousInjection

[Non-proprietaryname]Catridecacog(GeneticalRecombination)(JAN*)

[Applicant]NovoNordiskPharmaLtd.

[Dateofapplication]August29,2014

[Reviewresults]

InthemeetingheldonMarch5,2015,theSecondCommitteeonNewDrugsconcludedthattheproduct

maybeapprovedandthatitsresultshouldbepresentedtothePharmaceuticalAffairsDepartmentofthe

PharmaceuticalAffairsandFoodSanitationCouncil.

There-examinationperiodis10years.Neitherthedrugsubstancenorthedrugproductisclassifiedas

apoisonousdrugorapowerfuldrugandtheproductisnotclassifiedasabiologicalproductora

specifiedbiologicalproduct.

[Conditionsforapproval]

Theapplicantisrequiredto:

?Developandappropriatelyimplementariskmanagementplan.

?Conductause-resultssurveythatshouldcoverallJapanesepatientsreceivingtheproduct,toidentify

thecharacteristicsofpatientsreceivingtheproduct,tocollectefficacyandsafetydata,andtotake

appropriatemeasurestoensuretheproperuseoftheproduct,whereverpossible,sincethenumber

ofsubjectsenrolledintheJapaneseclinicalstudiesoftheproductisextremelylimited.Thesurvey

shouldbecontinuedforacertainperiodoftime.

*JapaneseAcceptedName(modifiedINN)

ThisEnglishversionoftheJapanesereviewreportisintendedtobeareferencematerialtoprovideconvenienc