基本信息
文件名称:STING-agonist-42-生命科学试剂-MCE.pdf
文件大小:455.76 KB
总页数:1 页
更新时间:2025-06-12
总字数:约1.81千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

STINGagonist-42

Cat.No.:HY-176126

CASNo.:2942231-48-1

分?式:C??H?F?LiN?O?

分?量:375.21

作?靶点:STING

作?通路:Immunology/Inflammation

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性STINGagonist-42(compound8a)是?种有效的STING激动剂。STINGagonist-42在THP1和RAW264.7细

胞中激活STING,EC50值分别为0.06和14.15μM。

REFERENCES

[1].HouH,etal.Discoveryof3-(Fluoro-imidazolyl)pyridazineDerivativesasPotentSTINGAgonistswithAntitumorActivity.JMedChem.

2025May9.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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