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N-Nitrosodiethylamine(Standard)

Cat.No.:HY-N7434R

CASNo.:55-18-5

Synonyms:Diethylnitrosamine(Standard);DEN(Standard)

分?式:C?H??N?O

分?量:102.14

作?靶点:ReferenceStandards;DNA/RNASynthesis

作?通路:Others;CellCycle/DNADamage

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性N-Nitrosodiethylamine(Standard)是N-Nitrosodiethylamine的分析标准品。本产品?于研究及分析应?。

N-Nitrosodiethylamine(Diethylnitrosamine)是?种有效的致癌物质?烷基硝胺。N-Nitrosodiethylamine主

要存在于烟草烟雾、?、切达?酪、腌制?品、油炸?品和许多酒精饮料中。N-Nitrosodiethylamine负责与

DNA修复/复制相关的核酶的变化。N-Nitrosodiethylamine可导致所有动物的各种肿瘤。主要靶器官为?腔、

?管、肺、?管和肝脏。

REFERENCES

[1].RamakrishnanG,etal.SuppressionofN-nitrosodiethylamineinducedhepatocarcinogenesisbysilymarininrats.ChemBiolInteract.

2006Jun10;161(2):104-14.

[2].BansalAK,etal.ProtectiveroleofVitaminEpre-treatmentonN-nitrosodiethylamineinducedoxidativestressinratliver.ChemBiol

Interact.2005Oct20;156(2-3):101-11.

[3].GombarCT,eta