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Insecticidalagent21

Cat.No.:HY-173413

CASNo.:3082443-45-3

分?式:C??H??ClN?O?

分?量:594.19

作?靶点:Insecticide;Cholinesterase(ChE);nAChR;SodiumChannel;

GABAReceptor

作?通路:Others;NeuronalSignaling;MembraneTransporter/Ion

Channel

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Insecticidalagent21(Compound6)是?种针对Culexpipiens幼?的杀?剂(LC50:0.4μg/mL)。

Insecticidalagent21通过抑制?酰胆碱酯酶(AChE)并同时靶向其他神经受体(烟碱?酰胆碱受体(nAChR)、

电压门控钠通道(VGSC)和γ-氨基丁酸受体(GABAAR))，实现多靶点神经毒性。Insecticidalagent21具有强

?的杀?效?，可?于新型杀?剂的开发，以应对蚊?对传统杀?剂的抗药性问题[1]。

REFERENCES

[1].El-HelwEAE,etal.SynthesisofBenzo[h]quinolinederivativesandevaluationoftheirinsecticidalactivityagainstCulexpipiensL.larvae.

EurJMedChem.2025Jun5;290:117565.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.