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Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

AMPTX-1

Cat.No.:HY-172615

CASNo.:3033019-04-1

分?式:C??H??N?O?

分?量:691.9

作?靶点:MolecularGlues;EpigeneticReaderDomain

作?通路:PROTAC;Epigenetics

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性AMPTX-1是?种分?胶，它是?种强效、选择性、可逆共价的BRD9降解剂，通过将BRD9募集到E3连接酶

DCAF16[1]上。

REFERENCES

[1].ScottJ.Hughes,etal.SelectivedegradationofBRD9byaDCAF16-recruitingtargetedglue:modeofactionelucidationandinvivoproof

ofconcept.bioRxiv.January02,2025.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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