Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
TAT-CN21(scrambled)
Cat.No.:HY-P10638A
分?式:C???H???N??O??
分?量:3989.65
Sequence:Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Val-Lys-Glu-Pro
-Arg-Ile-Asp-Gly-Lys-Pro-Val-Arg-Leu-Arg-Gly-Gln-Lys-Ser-As
p-Arg-Ile
SequenceShortening:YGRKKRRQRRRVKEPRIDGKPVRLRGQKSDRI
作?靶点:CaMK
作?通路:NeuronalSignaling
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性TAT-CN21(scrambled)是?种缺乏特定靶向活性的对照肽，作为TatCN21(HY-P10638)的阴性对照。
TatCN21是钙/钙调素依赖性蛋?激酶II(CaMKII)的有效选择性抑制剂肽[1]。
IC50TargetCaMKII
REFERENCES
[1].BuardI,etal.CaMKIIautonomyisrequiredforinitiatingbutnotformaintainingneuronallong-terminformationstorage.JNeurosci.
2010Jun16;30(24):8214-20.
[2].Tao-ChengJH,etal.EffectsofCaMKIIinhibitortatCN21onactivity-dependentredistributionofCaMKIIinhippocampalneurons.
Neuroscience.2013Aug6;244:188-96.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.