基本信息
文件名称:Ruboxyl-生命科学试剂-MCE.pdf
文件大小:467.01 KB
总页数:1 页
更新时间:2025-06-12
总字数:约2.05千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Ruboxyl

Cat.No.:HY-119261

CASNo.:80214-88-6

分?式:C??H??ClN?O??

分?量:731.23

作?靶点:Antibiotic

作?通路:Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Ruboxyl是?种蒽环类抗?素,具有抗肿瘤活性。Ruboxyl在??体内对结直肠癌(CRC)肝转移的抑制率为

84%,且可抑制B16??素瘤?长,并提?L1210或L5178Y??病的??的存活率[1][2]。

REFERENCES

[1].LeonettiC,etal.Ruboxyl,anewnitroxylderivativeofdaunorubicin-acutetoxicityandantitumoreffectinanimals.IntJOncol.1993

Oct;3(4):615-8.

[2].SirovichI,etal.Activityofruboxyl,anitroxylderivativeofdaunorubicin,onexperimentalmodelsofcolorectalcancermetastases.

TumourBiol.1999Sep-Oct;20(5):270-6.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1Master