基本信息
文件名称:P-gp-inhibitor-29-生命科学试剂-MCE.pdf
文件大小:463.52 KB
总页数:1 页
更新时间:2025-06-12
总字数:约1.88千字
文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

P-gpinhibitor29

Cat.No.:HY-173401

CASNo.:3082344-99-5

分?式:C??H??N?O?S

分?量:528.57

作?靶点:P-glycoprotein

作?通路:MembraneTransporter/IonChannel

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性P-gpinhibitor29(41)是?种?效的P-gp抑制剂和凋亡诱导剂,其在Eca109/VCR细胞中的IC50值为8.9

nM,可?于?管癌研究。

REFERENCES

[1].BoXu,etal.Design,synthesis,andbiologicalactivitystudyof6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinederivativesagainstmultidrug

resistanceinEca109/VCRcells.EurJMedChem.2025Jul5:291:117542.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师