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Inhibitors?ScreeningLibraries?Proteins
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HedgehogIN-9
Cat.No.:HY-176056
CASNo.:438488-95-0
分?式:C??H??N?O?S
分?量:358.45
作?靶点:Hedgehog;Gli;EpigeneticReaderDomain
作?通路:StemCell/Wnt;Epigenetics
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性HedgehogIN-9(compound1)是?种Hedgehog抑制剂。HedgehogIN-9能够抑制GLI1的表达,并增强细
胞中BRD2蛋?的?平。HedgehogIN-9可以抑制髓母细胞瘤球状细胞的?长,并可?于光亲和标记探针的合
成。
REFERENCES
[1].TsakoumagkosIA,etal.EvaluationofBenzo[cd]indol-2(1H)-onesasDownstreamHedgehogPathwayInhibitors.ChemistryOpen.2025
Apr14:e202500119.
McePdfHeight
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师