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FGFR1inhibitor-18
Cat.No.:HY-172618
分?式:C??H??ClN?O?
分?量:468.89
作?靶点:FGFR
作?通路:ProteinTyrosineKinase/RTK
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性FGFR1inhibitor-18(compound16)是?种有效的FGFR1抑制剂，IC50为1.31nM。FGFR1inhibitor-18可以
占据靶标FGFR1的ATP结合位点。
IC50TargetFGFR1
1.31nM(IC50)
REFERENCES
[1].RonnakornLeechaisit,etal.Design,Synthesis,BiologicalEvaluationandMolecularModelingStudiesofNovelNaphthoquinone-
TriazoleHybridsasPotentialFGFR1TyrosineKinaseInhibitors.AsianJournalofOrganicChemistry,2025:e202400813.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师