基本信息
文件名称:Cbz-S-S-Pro-Pro-allyl-生命科学试剂-MCE.pdf
文件大小:462.39 KB
总页数:1 页
更新时间:2025-06-12
总字数:约1.97千字
文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Cbz-(S,S)-Pro-Pro-allyl

Cat.No.:HY-172790

分?式:C??H??N?O?

分?量:386.44

作?靶点:COX;Lipoxygenase

作?通路:Immunology/Inflammation;MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Cbz-(S,S)-Pro-Pro-allyl(compound1a)是环氧合酶-2和5-脂氧合酶的双重抑制剂,对COX-1、COX-2和5-LOX

的IC50值分别为0.146nM、0.003nM和0.64nM。Cbz-(S,S)-Pro-Pro-allyl具有抗炎活性[1]。

REFERENCES

[1].ViveshVivesh,etal.ArationaleapproachindevelopingprolinebasedsmallpeptideasU-shapedanaloguesofarachidonicacid:Dual

inhibitorsofcyclooxygenase-2and5-lipoxygenasefordevelopinganti-inflammatoryagents.BioorgChem.2025Jun15:160:108452.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师