基本信息
文件名称:Apoptosis-inducer-37-生命科学试剂-MCE.pdf
文件大小:462.15 KB
总页数:1 页
更新时间:2025-06-12
总字数:约2.06千字
文档摘要

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Inhibitors?ScreeningLibraries?Proteins

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Apoptosisinducer37

Cat.No.:HY-172890

分?式:C??H??BrN?O?S

分?量:565.56

作?靶点:Apoptosis

作?通路:Apoptosis

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Apoptosisinducer37(Derivative10)是?种apoptosis诱导剂。Apoptosisinducer37通过诱导S-G2/M期细

胞周期阻滞和促进细胞凋亡发挥抗癌作?。Apoptosisinducer37对HCT116、SKOV3和HepG2癌细胞具有

显著抑制活性(IC50值分别为24.98μM、26.15μM和23.09μM)。Apoptosisinducer37具有抗肿瘤作?

,可?于卵巢癌研究[1]。

REFERENCES

[1].DingY,etal.SynthesisofIsosteviolderivativesaspotentialanticanceragents,especiallyforovarianCancer:Invitrocytotoxicity,cell

cyclearrest,networkpharmacologyandmoleculardockingstudy.BioorgMedChemLett.2025Apr29;124:130261.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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