Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
BisphenolB-d8
Cat.No.:HY-W653975
CASNo.:2469735-90-6
分?式:C??H??D?O?
分?量:250.36
作?靶点:Isotope-LabeledCompounds;EndogenousMetabolite
作?通路:Others;MetabolicEnzyme/Protease
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性BisphenolB-d8是BisphenolB(HY-W013935)的氘代物。BisphenolB是与BisphenolA(HY-18260)结构相
近的类似物。?BisphenolA是?种内分泌?扰化学物质(EDC)。BisphenolB对动物模型具有内分泌?扰性或
其他不良作?。
体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,
largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention
becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.
REFERENCES
[1].SerraH,etal.EvidenceforBisphenolBEndocrineProperties:ScientificandRegulatoryPerspectives.EnvironHealthPerspect.2019
Oct;127(10):106001.
[2].UllahA,etal.BisphenolAanditsanalogsbisphenolB,bisphe