临床研究（2）Vapreotide,anewsomatostatinanalogueinthepalliativemanagementofobstructiveileusinadvancedcancer.
StiefelF,MorantR.
DepartmentofMedicineC,Kantonsspital,St.Gallen,Switzerland.
SupportCareCancer.1993Jan;1(1):57-8.
*临床研究（3）Importanceofvasoactiveintestinalpeptideandsomatostatinforfluidlossesinsmall-bowelobstruction.
NellgardP,BojoL,CassutoJ.
Dept.ofAnaesthesiology,GoteborgUniversity,Sweden.
ScandJGastroenterol.1995May;30(5):464-9.*临床研究（4）VasoactiveintestinalpeptideandsubstancePreceptorantagonistsimprovepostoperativeileus.
EspatNJ,ChengG,KelleyMC,VogelSB,SninskyCA,HockingMP.
DepartmentofSurgery,UniversityofFloridaCollegeofMedicine,Gainesville,USA.
JSurgRes.1995Jun;58(6):719-23.*相关研究进展*研究进展（1）Effectsoflanreotideonthehealingofsmallbowelanastomosesfollowingobstructiveileusinrats.
DemetriadesH,KanellosI,MantzorosI,KalfadisS,GalovatseaK,ZaraboukasT,BetsisD.
4thSurgicalDepartment,AristotleUniversityofthessaloniki,G.PapanikolaouGeneralHospital,Thessaloniki,Greece.
ColorectalDis.2002Jan;4(1):23-27.*研究进展（1）结果实验组肠腔扩张情况轻于对照组。(P0.001)实验组电解质丢失轻于对照组。(P0.001)实验组组织学检查发现其血管吻合口的感染反应轻于对照组，但显微镜下观察伤口愈合程度几乎没有区别。*Intestinalwalldamageinsimpleileusinrabbits:immune-modulatorroleofsomatostatin.
Jimenez-GarciaA,Balongo-GarciaR,AlconeroFF,ArajiOA,MartinezGJ,HabaMG,MoralesLC,BeviaJM,MartinezJC.
DepartmentofSurgery,VirginMacarenaUniversityHospital,FacultyofMedicineUniversityofSeville,Spain.Hepatogastroenterology.2004Jul－Aug;51(58):1030-6.研究进展（2）*研究进展（2）结果生长抑素治疗组的肠腔损害情况明显轻于未治疗组。肠腔损害明显与TNF-α和IL-2水平升高有关，而与IL-6水平无关。生长抑素可对肠壁起到细胞保护作用，而且阻碍细胞免疫炎症介质的产生，但对体液免疫没有类似影响。*结论*生长抑素的作用减少胃肠道的分泌减轻梗阻近端肠腔内液体淤积和肠腔扩张利于肠壁水肿消退循环改善维持水、电解质平衡改善胃肠道的外科条件，利于手术，缩短手术时间减少术后肠管再次粘连、再梗阻*生长抑素在急性肠梗阻中的应用同济医院胃肠外科中心*肠梗阻的分类急缓：急性/慢性程度：完全/不完全位置：高位/低位血运：单纯/绞窄病因：动力性、机械性、血运性*急性