Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Pirarubicin(Hydrochloride)(Standard)

Cat.No.:HY-13725AR

CASNo.:95343-20-7

分?式:C??H??ClNO??

分?量:664.1

作?靶点:Topoisomerase;Autophagy;Bacterial;Antibiotic

作?通路:CellCycle/DNADamage;Autophagy;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Pirarubicin(Hydrochloride)(Standard)是Pirarubicin(Hydrochloride)的分析标准品。本产品?于研究及分析

应?。PirarubicinHydrochloride(THPHydrochloride)是?种蒽环类抗?素，为拓扑异构酶II

(topoisomeraseII)的抑制剂，可?于各种癌症尤其是实体瘤的研究。

IC50TargetTopoisomeraseII[1]

REFERENCES

[1].TakigawaN,etal.CytotoxiceffectoftopoisomeraseIIinhibitorsagainstadriamycin-andetoposide-resistantsmallcelllungcancer

sublines.GanToKagakuRyoho.1993May;20(7):929-35.

[2].NagaiK,etal.RelationshipsbetweentheinvitrocytotoxicityandtransportcharacteristicsofpirarubicinanddoxorubicininM5076

ovariansarcomacells,andcomparisonwiththoseinEhrlichascitescarcinomacells.CancerChemotherPharmacol.2002Mar;49(3):244-

50.Ep