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Mycoplasma *thesmallestfree-livingprokaryoticorganismthatcan growinartificialmedia *non-cellwall,pleomorphism Mycoplasma Biological Properties 1.size:0.2~0.3μm,passthrough0.45filters 2.polymorphic:–non-cellwall coccoid,baculiform,filamentous… 3.Giemsastain:purple Microbiology.A Human Perspective.McGraw-Hill.7th(2012) P62 FIG3.34 Mycoplasma Biological Properties 4.structure threelayerofmembrane twoproteinmembrane,onelipidmembrane terminalstructure: somemycoplasmahavespecializedstructuresatoneorbothendsby whichtheyadheretorespiratoryorgenitaltractmucoussurfaces Microbiology.A Human Perspective.McGraw-Hill.7th(2012) P500 FIGURE 21.14 Mycoplasma Biological Properties 5.culture *highnutrient:10~20%serum *slowlygrowth:2~3weeksfried-eggcolony 6.classification mycoplasma Microbiology.A Human Perspective.McGraw- ureaplasma Hill.7th(2012) P276 FIG 11.26 7.resistant *weak *sensitivetostreptomycin,erythromycin,tetracycline *resistanttopenicillin,cephalosporin Mycoplasma Pathogenicity 1. Mycoplasma pneumoniae [MP] 2. Ureaplasma urealyticum [UU] Mycoplasma Pathogenicity 1.Mycoplasmapneumoniae →primaryatypicalpneumonia[PAP] *spreadbyrespiratory,incubation2~3weeks; interstitialpneumonia *headache,cough,fever,malaise; *ery
Mycoplasma *thesmallestfree-livingprokaryoticorganismthatcan growinartificialmedia *non-cellwall,pleomorphism Mycoplasma Biological Properties 1.size:0.2~0.3μm,passthrough0.45filters 2.polymorphic:–non-cellwall coccoid,baculiform,filamentous… 3.Giemsastain:purple Microbiology.A Human Perspective.McGraw-Hill.7th(2012) P62 FIG3.34 Mycoplasma Biological Properties 4.structure threelayerofmembrane twoproteinmembrane,onelipidmembrane terminalstructure: somemycoplasmahavespecializedstructuresatoneorbothendsby whichtheyadheretorespiratoryorgenitaltractmucoussurfaces Microbiology.A Human Perspective.McGraw-Hill.7th(2012) P500 FIGURE 21.14 Mycoplasma Biological Properties 5.culture *highnutrient:10~20%serum *slowlygrowth:2~3weeksfried-eggcolony 6.classification mycoplasma Microbiology.A Human Perspective.McGraw- ureaplasma Hill.7th(2012) P276 FIG 11.26 7.resistant *weak *sensitivetostreptomycin,erythromycin,tetracycline *resistanttopenicillin,cephalosporin Mycoplasma Pathogenicity 1. Mycoplasma pneumoniae [MP] 2. Ureaplasma urealyticum [UU] Mycoplasma Pathogenicity 1.Mycoplasmapneumoniae →primaryatypicalpneumonia[PAP] *spreadbyrespiratory,incubation2~3weeks; interstitialpneumonia *headache,cough,fever,malaise; *ery