叶酸结合依诺肝素钠对子痫前期并胎儿生长受限患者胎儿生长发育及妊娠结局的影响\o分享到微博\o分享到微信\o分享到QQ\o分享到QQ空间
【摘要】目的:探讨叶酸结合依诺肝素钠对子痫前期并胎儿生长受限患者胎儿生长发育及妊娠结局的影响。方法:研究开始时间2021年6月,结束时间2023年5月,收集本院此区间内收治的子痫前期并胎儿生长受限患者,共88例,以信封法分组,即对照组(n=44)和观察组(n=44)。前者予以依诺肝素钠治疗,后者联用依诺肝素钠和叶酸治疗。对比两组胎儿生长发育、血压水平及妊娠结局。结果:治疗后,观察组胎儿生长发育各项指标均优于对照组,血压水平低于对照组,剖宫产(4.55%)、早产(4.55%)以及产后出血(0.00%)发生率均低于对照组(20.45%、18.18%以及15.91%),P0.05。结论:联合用药有利于胎儿生长发育,改善妊娠结局,效果确切。
【关键词】子痫前期;胎儿生长受限;叶酸;依诺肝素钠;生长发育;妊娠结局
Effectsoffolicacidcombinedwithenoxaparinsodiumonfetalgrowthanddevelopmentandpregnancyoutcomesinpatientswithpreeclampsiaandfetalgrowthrestriction
SHANGLiqiong
BaiyinFirstPeople’sHospitalofGansu,Baiyin,Gansu730900,China
【Abstract】Objective:Toinvestigatetheeffectsoffolicacidcombinedwithenoxaparinsodiumonfetalgrowthanddevelopmentandpregnancyoutcomesinpatientswithpreeclampsiaandfetalgrowthrestriction.Methods:ThestudybeganinJune2021andendedinMay2023.Atotalof88patientswithpreeclampsiaandfetalgrowthrestrictionadmittedtoourhospitalwithinthisintervalwerecollectedanddividedintothecontrolgroup(n=44)andtheobservationgroup(n=44)bytheenvelopemethod.Theformerwastreatedwithenoxaparinsodium,andthelatterwastreatedwithacombinationofenoxaparinsodiumandfolicacid.Thefetalgrowthanddevelopment,bloodpressurelevelsandpregnancyoutcomeswerecomparedbetweenthetwogroups.Results:Aftertreatment,thefetalgrowthanddevelopmentindexesintheobservationgroupwerebetterthanthoseinthecontrolgroup,bloodpressurelevelswerelowerthanthoseinthecontrolgroup,andtheratesofcesareansection(4.55%),pretermdelivery(4.55%),andpostpartumhemorrhage(0.00%)werelowerthanthoseinthecontrolgroup(20.45%,18.18%and15.91%),P0.05.Conclusion:Combineddrugisbeneficialtofetalgrowthanddevelopment,improvepregnancyoutcomes,andtheeffectisaccurate.
【KeyWords】Preeclampsia;Fetalgrowthrestriction;Folicacid;Enoxa