门冬胰岛素配合地特胰岛素治疗妊娠期糖尿病的疗效评价\o分享到微博\o分享到微信\o分享到QQ\o分享到QQ空间
【摘要】目的:研讨在妊娠期糖尿病治疗中,门冬胰岛素配合地特胰岛素的效果。方法:选取妊娠期糖尿病患者80例,样本选取时间为2022年8月—2024年8月,按照随机数字表法分组,每组样本数量为40例,对照组给予门冬胰岛素治疗,研究组给予门冬胰岛素配合地特胰岛素治疗。比较两组胰岛素使用情况、血糖达标时间、血糖指标、胰岛细胞功能、治疗效率以及不良妊娠结局发生率。结果:研究组血糖达标时间短于对照组,胰岛素用量和注射次数低于对照组(P0.05);治疗后,两组血糖指标均得到有效改善,且研究组血糖指标水平均低于对照组,对比有意义(P0.05);治疗后,研究组胰岛细胞功能指标较对照组更佳(P0.05);研究组不良妊娠结局发生率较对照组更低,统计学分析有意义(P0.05);研究组治疗总有效率高于对照组(P0.05)。结论:门冬胰岛素配合地特胰岛素疗效高,可以帮助患者改善胰岛细胞功能,对血糖控制有积极意义,降低不良妊娠结局发生率,利于疾病转归。
【关键词】妊娠期糖尿病;门冬胰岛素;地特胰岛素;不良妊娠结局;血糖达标时间;胰岛细胞功能;治疗效率
Evaluationoftheefficacyofinsulinaspartcombinedwithinsulindetemirintreatinggestationaldiabetesmellitus
SUNLixia
QingyangMaternalandChildHealthCareHospital,Qingyang,Gansu745000,China
【Abstract】Objective:Todiscusstheeffectofinsulinaspartcombinedwithinsulindetemirinthetreatmentofgestationaldiabetes.Methods:80casesofgestationaldiabetesmellituspatientswereselectedfromAugust2022toAugust2024,theyweredividedintogroupsaccordingtotherandomnumbertablemethod,withasamplesizeof40casesineachgroup.Thecontrolgroupwastreatedwithinsulinaspart,andthestudygroupwastreatedwithinsulinaspartcombinedwithinsulindetemir.Theinsulinusecase,timeofbloodglucosecompliance,bloodglucoseindexes,isletcellfunction,treatmentefficiency,andincidenceofadversepregnancyoutcomesbetweentwogroupswerecompared.Results:Thebloodglucosecompliancetimeinthestudygroupwasshorterthanthatinthecontrolgroup,insulindosageandinjectiontimeswerelowerthanthoseinthecontrolgroup(P0.05);Aftertreatment,thebloodglucoseindexesofbothgroupswereeffectivelyimproved,andthebloodglucoseindexeslevelsofthestudygroupwerelowerthanthoseofthecontrolgroup(P0.05);Aftertreatment,theisletcellfunctionindexesinthestudygroupwerebetterthanthoseinthecontrolgroup(P0.05);Theincidenceofadversepregnancyoutcomesinthestudygroupwaslower