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Gentisuricacid(Standard)

Cat.No.:HY-W338852R

CASNo.:25351-24-0

分?式:C?H?NO?

分?量:211.17

作?靶点:DrugMetabolite

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Gentisuricacid(Standard)是Gentisuricacid的分析标准品。本产品?于研究及分析应?。GentisuricAcid是

阿司匹林(Aspirin(HY-14654))的代谢产物，也是α-酰胺化单加氧酶(PAM)的底物。GentisuricAcid可防?

MitomycinC(HY-13316)造成的DNA损伤。

REFERENCES

[1].DeBlassioJL,etal.Amidationofsalicyluricacidandgentisuricacid:apossibleroleforpeptidylglycinealpha-amidatingmonooxygenase

inthemetabolismofaspirin.ArchBiochemBiophys.2000Nov1;383(1):46-55.

[2].NiikawaM,etal.Suppressiveeffectofpost-orpre-treatmentofaspirinmetaboliteonmitomycinC-inducedgenotoxicityusingthe

somaticmutationandrecombinationtestinDrosophilamelanogaster.BiomedPharmacother.2007Feb-Apr;61(2-3):113-9.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.