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Cholesterylhemisuccinate(Standard)

Cat.No.:HY-W010800R

CASNo.:1510-21-0

分?式:C??H??O?

分?量:486.73

作?靶点:Topoisomerase;DNA/RNASynthesis;Apoptosis;Necroptosis

作?通路:CellCycle/DNADamage;Apoptosis

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Cholesterylhemisuccinate(Standard)是Cholesterylhemisuccinate的分析标准品。本产品?于研究及分析

应?。Cholesterylhemisuccinate是?种具有保肝和抗癌活性的物质。Cholesterylhemisuccinate抑制对?酰

氨基酚(AAP,HY-66005)的肝毒性，并防?AAP诱导的肝细胞凋亡(apoptosis)和坏死(necrosis)。

Cholesterylhem

REFERENCES

[1].RaySD,etal.Protectionofacetaminophen-inducedhepatocellularapoptosisandnecrosisbycholesterylhemisuccinatepretreatment.J

PharmacolExpTher.1996Dec;279(3):1470-83.

[2].VarshosazJ,etal.Folatedsynperonic-cholesterylhemisuccinatepolymericmicellesforthetargeteddeliveryofdocetaxelinmelanoma.

BiomedResInt.2015;2015:746093.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.