122JModUrol,Vol.30No.2Feb.2025
·临床研究·
前列腺穿刺活检术术后感染的危险因素分析及预测模型建立
孙朋浩，宋伟
（山东第一医科大学附属省立医院泌尿外科，山东济南250000）
Analysisofriskfactorsandestablishmentofapredictionmodelforinfectionafter
prostatebiopsy
SUNPenghao,SONGWei
(DepartmentofUrology,ShandongProvincialHospitalAffiliatedtoShandongFirstMedicalUniversity,
Jinan250000,China)
ABSTRACT:Objective
eToanalyzetheriskfactorsleadingtoinfectionafterprostatebiopsy,establishanomogram
predictionmodelandverifyit.MethodsClinicaldataof523patientswhounderwentultrasound-guidedprostatebiopsyatour
hospitalduringJan.2023andJul.2024wereretrospectivelyanalyzed.Patientsweredividedintoaninfectiongroupandanon-
infectiongroup.Independentriskfactorsforinfectionafterprostatebiopsywereidentifiedwithunivariateandmultivariate
binarylogisticregressionanalyses,andanomogrampredictionmodelwasconstructed,whichwasvalidatedwithreceiver
operatingcharacteristic(ROC)curve,calibrationcurve,anddecisioncurveanalysis(DCA).ResultsInfectionoccurredin54
cases(10.3%).Univariateandmultivariatelogisticregressionanalysesshowedthatage65years(OR=3.535,P=0.003),
diabetes(OR=5.693,P0.001),hypoproteinemia(OR=8.936,P0.001),preoperativeurinarytractinfection(OR
6.153,P0.001),punctureneedles12(OR=4.347,P0.001),andtransrectalpuncture(OR=3.701,P0.001)were
independentriskfactorsforinfection.Basedonthemultivariatelogisticanalysisresults,ariskpredictionnomogrammodelwas
constructed,withanareaundertheROCcurve(AUC)of0,894.ThecalibrationcurveandDCAbothindicatedthatthemodel
hadhighpredictiveaccuracyandclinicaldecision-makingefficiency.ConclusionAge65years,diabetes,hypoproteinemia,
preoperativeurinarytractinfection,punctureneedles12,andtransrectalpunctureareind