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Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

RORγtinhibitor4

Cat.No.:HY-19510

CASNo.:1426803-07-7

分?式:C??H??Cl?F?NO?S

分?量:518.33

作?靶点:ROR

作?通路:MetabolicEnzyme/Protease;VitaminDRelated/Nuclear

Receptor

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性RORγtinhibitor4(Compound9a)是?种?服活性且可穿透中枢神经系统的RORγt抑制剂。RORγt

inhibitor4可改善实验性??免疫性脑脊髓炎[1]。

IC50TargetRORγt

REFERENCES

[1].WangY,etal.DiscoveryofBiarylAmidesasPotent,OrallyBioavailable,andCNSPenetrantRORγtInhibitors.ACSMedChemLett.

2015May26;6(7):787-92.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您?边的抑制剂?师