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Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
2-Heptyl-4-quinolone-15N
Cat.No.:HY-129503S1
分?式:C??H????NO
分?量:244.34
作?靶点:Isotope-LabeledCompounds;DrugIntermediate
作?通路:Others
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性2-Heptyl-4-quinolone-15N是15标记的2-Heptyl-4-quinolone(HY-129503)。2-Heptyl-4-quinolone是合成
喹诺酮假单胞菌信号(PQS)的中间体,通过正向调节phenazine的产?来控制群集运动。2-Heptyl-4-
quinolone诱导phenazine-1-carboxylicacid(PCA)的?成。
体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,
largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention
becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.
REFERENCES
[1].HaDG,etal.2-Heptyl-4-quinolone,aprecursorofthePseudomonasquinolonesignalmolecule,modulatesswarmingmotilityin
Pseudomonasaeruginosa.JBacteriol.2011Dec;193(23):6770-80.
McePdfHeight
Caution:Producthasnotbeenfully