基本信息
文件名称:2-Heptyl-4-quinolone-15N-生命科学试剂-MCE.pdf
文件大小:457.73 KB
总页数:1 页
更新时间:2025-03-15
总字数:约2.38千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

2-Heptyl-4-quinolone-15N

Cat.No.:HY-129503S1

分?式:C??H????NO

分?量:244.34

作?靶点:Isotope-LabeledCompounds;DrugIntermediate

作?通路:Others

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性2-Heptyl-4-quinolone-15N是15标记的2-Heptyl-4-quinolone(HY-129503)。2-Heptyl-4-quinolone是合成

喹诺酮假单胞菌信号(PQS)的中间体,通过正向调节phenazine的产?来控制群集运动。2-Heptyl-4-

quinolone诱导phenazine-1-carboxylicacid(PCA)的?成。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].HaDG,etal.2-Heptyl-4-quinolone,aprecursorofthePseudomonasquinolonesignalmolecule,modulatesswarmingmotilityin

Pseudomonasaeruginosa.JBacteriol.2011Dec;193(23):6770-80.

McePdfHeight

Caution:Producthasnotbeenfully