浙江临床医学2025年1月第27卷第1期·127·
·流行病学调查·
兰溪市肺癌高危人群分布及影响因素分析
施昕朱梦叶青诸葛文嵩王英臣胡立翔陈慧卿郑慧君吴夏秋郑卫方*
【摘要】目的调查兰溪市6个村肺癌高危人群的分布，分析影响因素。方法2023年1月至2023年12月采取整群抽样方法，在兰溪市6个
村庄抽取≥45岁的2360例居民进行问卷调查，通过Logistic回归分析，亚组分析、敏感性分析，分析肺癌高危人群分布及影响因素。结果调
查者中肺癌高危人数662例，其中女290例，男372例。Logistic回归分析显示，年龄、腰围、BMI、运动、吸烟、慢性肺病、高血脂、癌症家族
史、幽门螺旋杆菌（HP）感染、脾虚等是肺癌危险因素。女性年龄每增加1岁，肺癌高危风险增加4%；男性中吸烟者肺癌高危风险是非吸烟
者1.67倍。结论肺癌高危影响因素较多，明确肺癌高危因素，有望提高肺癌早期筛查准确性和临床干预有效性。
【关键词】肺癌多癌筛查高危人群兰溪影响因素
【Abstract】ObjectiveToinvestigatethedistributionofhigh-riskpopulationforlungcancerinLanxiCityandanalyzetheinfluencingfactors.
MethodsFromJanuary2023toDecember2023,aclustersamplingmethodwasadoptedtoselect2360residentsaged≥45from6villagesinLanxiCity
forquestionnairesurvey.Logisticregressionanalysis,subgroupanalysis,andsensitivityanalysiswereusedtoanalyzethedistributionandinfluencingfactors
ofhigh-riskpopulationsforlungcancer.ResultsAmongthesubjects,therewere662high-riskindividuals,including290femalesand372males.Logistic
Regressionanalysisshowedthatage,waistcircumference,bodymassindex(BMI),sports,smoking,chroniclungdisease,hyperlipidemia,familyhistoryof
cancer,helicobacterpylori(HP)infection,spleendeficiencywereallriskfactorsforlungcancer.Foreveryoneyearincreasedinfemaleage,theriskoflung
cancerincreasedby4%.Theriskoflungcanceramongmalesmokerswas1.67timeshigherthanthatofnon-smokers.ConclusionTherearemanyhigh-
riskfactorsforlungcancer,andidentifyingthesefactorsisexpectedtoimprovetheaccuracyofearlyscreeningforlungcancerandtheeffectivenessofclinical
interventions.
【Keywords】LungcancerMulticancerscreeningHigh-riskpopulationLanxiInfluencefactor