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Inhibitors?ScreeningLibraries?Proteins
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HypocrellinA(Standard)
Cat.No.:HY-N2575R
CASNo.:77029-83-5
分?式:C??H??O??
分?量:546.52
作?靶点:PKC;Bacterial;Parasite;HIV;VSV;VEGFR;Bcl-2Family;
Apoptosis
作?通路:Epigenetics;TGF-beta/Smad;Anti-infection;ProteinTyrosine
Kinase/RTK;Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性HypocrellinA(Standard)是HypocrellinA的分析标准品。本产品?于研究及分析应?。HypocrellinA是?种
PKC抑制剂，通过逆转?糖对内?素(ET-1)的表达来发挥抗糖尿病活性。HypocrellinA也是?种具有抗癌
，抗菌和抗病毒活性，特别是针对?类免疫缺陷病毒（HIV）的光动?疗法(PDT)光敏剂。此外，Hypocrellin-
A还拥有抗利什曼原?活性(IC50=0.27
IC50TargetPKC[1]
REFERENCES
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2019May;95(3):812-822.
[3].FehrMJ,etal.Rolesofoxygenandphotoinducedacidificationinthelight-dependentantiviralactivityofhypocrellinA.Biochemistry.
1995Dec5;34(48):15845-8.
[4].MaG,etal.Antimicrobialandantileishmanialactivitiesofh