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文件名称:D-二聚体和凝血4项检测在孕妇产前检查中的应用.docx
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更新时间:2025-03-15
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D-二聚体和凝血4项检测在孕妇产前检查中的应用\o分享到微博\o分享到微信\o分享到QQ\o分享到QQ空间

【摘要】目的:探究凝血4项和D-二聚体检测在孕妇产前检查中的临床价值。方法:选取2022年1月—2023年10月我院接受产前检查的妊高症(妊娠期高血压)孕妇40例作为试验对象,设为试验组,另选择同期40例接受产前检查的正常孕妇作为对照组,所有孕妇均进行凝血4项联合D-二聚体检测,对比两组不同孕期的D-二聚体、血清凝血酶原时间、活化部分凝血活酶时间、凝血酶时间及纤维蛋白原。结果:两组孕早期D-二聚体水平对比无差异(P0.05);孕晚期,试验组D-二聚体水平高于对照组,具有统计学差异(P0.05)。两组孕早期PT、APTT、TT及FIB对比无差异(P0.05);孕晚期,试验组APTT及PT短于对照组,FIB高于对照组,具有统计学差异(P0.05);孕晚期,两组TT比较无差异(P0.05)。结论:凝血4项联合D-二聚体检测在孕妇产前检查中效果显著,可以辅助诊断疾病,为后续分娩提供参考价值。

【关键词】产前检查;凝血4项;D-二聚体

TheapplicationofD-dimerandcoagulationfouritemsintheprenatalexaminationofpregnantwomen

XUWenjia

JiangyinPeople’sHospital,Jiangyin,Jiangsu214400,China

【Abstract】Objective:ToexploretheclinicalvalueoffourcoagulationtestsandD-dimerdetectioninprenatalexaminationofpregnantwomen.Methods:FortypregnantwomenwithGH(gestationalhypertension)whounderwentprenatalexaminationsinourhospitalfromJanuary2022toOctober2023wereselectedastheexperimentalgroup,andanother40normalpregnantwomenwhounderwentprenatalexaminationsduringthesameperiodwereselectedasthecontrolgroup.AllpregnantwomenunderwentfourcoagulationtestscombinedwithD-dimerdetection.TheD-dimer,serumprothrombintime,activatedpartialthromboplastintime,thrombintime,andfibrinogenwerecomparedbetweenthetwogroupsatdifferentstagesofpregnancy.Results:TherewasnodifferenceinthelevelsofD-dimerbetweenthetwogroupsinearlypregnancy(P0.05);Inlatepregnancy,theD-dimerlevelsintheexperimentalgroupwerehigherthanthoseinthecontrolgroup,withstatisticaldifferences(P0.05).TherewasnodifferenceinPT,APTT,TTandFIBbetweenthetwogroupsinearlypregnancy(P0.05);Inlatepregnancy,theAPTTandPTintheexperimentalgroupwereshorterthanthoseinthecontrolgroup,whiletheFIBwashigherthanthatinthecontrolgroup,withstatisticaldifferences(P0.05);Inlatepregnancy,therewasnodifferenceinTTbetweenthetwogroups(P0.05).