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Taprostenesodium

Cat.No.:HY-106699

CASNo.:87440-45-7

Synonyms:CG4203sodium

分?式:C??H??NaO?

分?量:420.47

作?靶点:ProstaglandinReceptor;nAChR

作?通路:GPCR/GProtein;MembraneTransporter/IonChannel;

NeuronalSignaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Taprostenesodium是前列腺素类prostacyclin(IP)受体的部分激动剂。Taprostenesodium与Prostaglandin

E2(PGE2)(HY-101952)、ONO-AE1-259(选择性EP2激动剂)和?酰胆碱相互作?。Taprostenesodium具有

显著的?脏保护作?[1]。

REFERENCES

[1].ChanKM,etal.PartialagonismoftaprosteneatprostanoidIPreceptorsinvascularpreparationsfromguinea-pig,rat,andmouse.J

CardiovascPharmacol.2004Jun;43(6):795-807.

[2].JohnsonG,etal.Endotheliumandmyocardialprotectingactionsoftaprostene,astableprostacyclinanalogue,afteracutemyocardial

ischemiaandreperfusionincats.CircRes.1990May;66(5):1362-70.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications