基本信息
文件名称:E3-Ligase-Ligand-linker-Conjugate-168-生命科学试剂-MCE.pdf
文件大小:454.02 KB
总页数:1 页
更新时间:2025-03-18
总字数:约1.86千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

E3LigaseLigand-linkerConjugate168

Cat.No.:HY-168911

分?式:C??H??BrN?O?

分?量:521.4

作?靶点:E3LigaseLigand-LinkerConjugates

作?通路:PROTAC

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性E3LigaseLigand-linkerConjugate168是有E3连接酶Cereblon的配体(HY-W249500)和连接?组成的复合

物。E3LigaseLigand-linkerConjugate168可以?于合成PROTACc-Metdegrader-3(HY-168910)[1]。

REFERENCES

[1].QiuX,etal.,RationalDesign,Synthesis,andBiologicalEvaluationofNovelc-MetDegradersforLungCancerTherapy.JMedChem.

2025Feb13;68(3):2815-2839.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您?边的抑制剂?师