ChineseJournalofCellBiology2013,35(7):907–915
DOI:10.11844/cjcb.2013.07.9002
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/kxyj/yjdy/zxgxb/200907/1909356.html
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(embryonicstemcells,ESCs)(pluripotency)
(hematopoiesis),ESCs,
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ESCs
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HematopoieticDifferentiationofEmbryonicStemCells
1,2221
WangZhen,DingXiaodan,ZhangYan,YuanJinduo
1
(CollegeofLifeSciences,ShandongNormalUniversity,Jinan200014,China;
2InstitutPasteurofShanghai,ChineseAcademyofSciences,Shanghai200025,China)
AbstractTheembryonicstemcells(ESC)havebeensuccessfullyusedtostudythedevelopmentofthe
hematopoieticcelllineages.Duringthepastdecades,anincreasingnumberofstudieshavedemonstratedthein
vitrohematopoieticdifferentiationsystemsofbothmouseandhumanESCcells,whichprovideusefultoolsfor
elucidatingtheregulationofhematopoieticdevelopment.Inthisreview,wesummarizetherecentprogressinthe
hematopoieticdifferentiationfrompluripotentembryonicstemcells.
Keywordshematopoiesis;embryonicstemcells;invitrodifferentiation
(:1
*Tel/Fax:021E-mail:yan_zhang@1981,EvansKaufmanMartin[1]
ThisworkwassupportedbytheNationalNaturalScienceFoundationof(embryonicstemcells,ESCs)
China(GrantNo