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2-Methylquinazolin-4-ol(Standard)

Cat.No.:HY-W051513R

CASNo.:1769-24-0

分?式:C?H?N?O

分?量:160.18

作?靶点:PARP

作?通路:CellCycle/DNADamage;Epigenetics

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性2-Methylquinazolin-4-ol(Standard)是2-Methylquinazolin-4-ol的分析标准品。本产品?于研究及分析应?

。2-Methylquinazolin-4-ol是?种?效、竞争性的poly(ADP-ribose)synthetase抑制剂，其Ki值为1.1μ

M。2-Methylquinazolin-4-ol是哺乳动物天冬氨酸氨基转移酶(ATCase)抑制剂，其IC

REFERENCES

[1].SYoshida,etal.Productionof2-methyl-4[3H]-quinazolinone,aninhibitorofpoly(ADP-ribose)synthetase,bybacterium.JAntibiot

(Tokyo).1991Jan;44(1):111-2.

[2].MahmoudBalbaa,etal.Inhibitionofmammalianaspartatetranscarbamylasebyquinazolinonederivatives.JEnzymeInhibMedChem.

2008Aug;23(4):483-92.

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