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L-Pipecolicacid(Standard)

Cat.No.:HY-W012734R

CASNo.:3105-95-1

分?式:C?H??NO?

分?量:129.16

作?靶点:EndogenousMetabolite

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性L-Pipecolicacid(Standard)是L-Pipecolicacid的分析标准品。本产品?于研究及分析应?。L-Pipecolicacid

(H-HoPro-OH)是?种具有?服活性的赖氨酸的分解产物，它能在患有常染?体遗传性疾病的婴?体液中积累

，?如Zellweger综合征，新??肾上腺机能障碍。L-Pipecolicacid可通过增强蛋?合成来促进肌?细胞的健

康和?长，并在促进肠道健康中发挥?定的作?。L-Pipecolicacid有望?于代谢紊乱、肌??长障碍、肠道疾

病等领域的研究。

体外研究L-Pipecolicacid(100μM,30minutes)significantlyincreasestherateofproteinsynthesisinC2C12

myotubes,showingstrongereffectsthanL-lysine(HY-N0469)[3].

WesternBlotAnalysis[3]

CellLine:C2C12myotubes(skeletalmuscle,C2C12mouse)

Concentration:100μM

IncubationTime:30min

Result:Significantlysuppressedtherateofproteindegradationandautophagyactivity,withno

effectontheubiquitin-proteasomalsystem.

体内研究L-Pipecolicacid(250mg/kg,p.o.,onceaday,for7days)improvesintestinalmotilityinloperamide