Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Ferulicacid(sodium)(Standard)

Cat.No.:HY-N0060AR

CASNo.:24276-84-4

分?式:C??H?NaO?

分?量:216.17

作?靶点:FGFR;EndogenousMetabolite;ReactiveOxygenSpecies

作?通路:ProteinTyrosineKinase/RTK;MetabolicEnzyme/Protease;

Immunology/Inflammation;NF-κB

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Ferulicacid(sodium)(Standard)是Ferulicacid(sodium)的分析标准品。本产品?于研究及分析应?。

Ferulicacidsodium是?种新型的成纤维细胞?长因?受体1(FGFR1)抑制剂,对于FGFR1和FGFR2的IC50值

分别为3.78and12.5μM。

IC50TargetIC50:3.78μM(FGFR1),12.5μM(FGFR2)[1].

REFERENCES

[1].YangGW,etal.FerulicAcidExertsAnti-AngiogenicandAnti-TumorActivitybyTargetingFibroblastGrowthFactorReceptor1-Mediated

Angiogenesis.IntJMolSci.2015Oct12;16(10):24011-31.

[2].ZeniAL,etal.Ferulicacidexertsantidepressant-likeeffectinthetailsuspensiontestinmice:evidencefortheinvolvementofthe

serotonergicsystem.EurJPharmacol.2012Mar15;679(1-3):68-74.

McePdfHeight