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BoerelasinE
Cat.No.:HY-N15306
分?式:C??H??NO?
分?量:477.59
作?靶点:Apoptosis
作?通路:Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性BoerelasinE是第?个可以从内?真菌Boeremiaexigua中分离得到的具有顺式构型Δ21(22)双键的细胞松弛
素。BoerelasinE对MCF-7细胞的抗增殖活性(IC50=20.52μM)?顺铂(HY-17394)更强。BoerelasinE通过
将MCF-7细胞停滞在G2/M期并诱导细胞凋亡来抑制MCF-7细胞的完全细胞分裂。
REFERENCES
[1].TianC,etal.DiscoveryofhighlyoxygenatedcytochalasanswithantiproliferativeactivityfromanendophyticfungusBoeremiaexigua.
BioorgChem.2025Mar;156:108198.
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