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Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

ML-B01

Cat.No.:HY-168915

分?式:C??H??Cl?N?O

分?量:476.44

作?靶点:Akt;PKA

作?通路:PI3K/Akt/mTOR;StemCell/Wnt;TGF-beta/Smad

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性ML-B01是?服有效的Akt和PKA抑制剂，IC50分别为2nM和136nM。ML-B01在??脑中表现出良好的?

脑屏障(BBB)通透性[1]。

IC50TargetIC50:2nM(Akt),136nM(PKA)

REFERENCES

[1].WuY,etal.,PharmacodynamicsofAktdrugsrevealedbyakinase-modulatedbioluminescentindicator.NatChemBiol.2025Feb11.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师