Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
13-TP
Cat.No.:HY-168473
分?式:C??H??F?N?O??P?
分?量:570.23
作?靶点:SARS-CoV;DNA/RNASynthesis
作?通路:Anti-infection;CellCycle/DNADamage
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性13-TP是?种SARS-CoV-2抑制剂。13-TP能有效抑制SARS-CoV-2中?复制转录复合体(C-RTC，nsp12-nsp7-
nsp82)催化的体外RNA合成(RNAsynthesis)。13-TP完全抑制RdRp聚合酶活性，并阻断部分引物RNA的完
全延伸。
REFERENCES
[1].LiangL,etal.Discoveryofa2-α-Fluoro-2-β-C-(fluoromethyl)PurineNucleotideProdrugasaPotentialOralAnti-SARS-CoV-2Agent.J
MedChem.2025Jan23;68(2):1994-2007.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
1/1MasterofBioactiveMolecules—您?边的抑制剂?师